Contains per ml:
Amoxicillin trihydrate ……………. 100 mg.
Neomycin sulphate ………………… 50 mg.
Solvents ad ……………………………. 1 ml.
Treatment of clinical mastitis caused by amoxicillin and neomycin sensitive micro-organisms like,
Corynebacterium, E. coli, Staphylococcus and Streptococcus spp.
The combination of amoxycillin and neomycin acts additive. Amoxicillin is a semisynthetic broadspectrum
penicillin with a bactericidal action against both Gram-positive and Gram-negative
bacteria. The range of effect includes Campylobacter, Clostridium, Corynebacterium, E. coli,
Erysipelothrix, Haemophilus, Pasteurella, Salmonella, Streptococcus spp. and penicil-linasenegative
Staphylococcus. The bactericidal action is due to inhibition of cell wall synthesis.
Neomycin is an aminoglycoside with a bactericidal action against mainly Gram-negative bacteria
like E. coli, Klebsiella, Pasteurella and Salmonella spp.
Hypersensitivity to amoxicillin and/or neomycin.
Administration in subtherapeutic doses.
Concurrent administration of tetracyclines, chloramphenicol, macrolides and lincosamides.
Administration to animals with a seriously impaired renal and/or hepatic function.
Overdosages because of the small safety margin of neomycin.
For intramammary administration:
Daily 1 injector per affected quarter for maximally 3 days.
Before application quarters have to be fully stripped and teats have to be cleaned and
disinfected.
– For meat: 5 days.
– For milk: 3 days.
Hypersensitivity reactions.
Renal dysfunction, neurotoxicity and neuromuscular blockade.
